Main Psyconeurological Disorders Affecting Gastrointestinal Functions
PSYCHIC
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Psychiatric disorders
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Somatization*
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Health anxiety*
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Conversion syndrome*
BRAIN
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Cerebrovascular accidents (USA: 400,000; GI Dysfunctions > 40%)
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Head injury
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Movement disorders (Parkinsonism) (70-180/100,000; GI Dysfunctions > 55%)
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Multiple sclerosis (USA: 250,000; GI Dysfunctions 68%)
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Cerebral Palsy -Alzheimer’s d (4% population > 65 yrs)
SPINAL CORD
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Traumatic lesions
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Spina bifida (1-4/1,000 live births; GI Dysfunctions > 75%)
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Multiple sclerosis (USA: 250,000; GI Dysfunctions 68%)
AUTONOMIC NERVOUS SYSTEM
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Sympathetic dysfunction *
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Parasympathetic dysfunction *
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Dorsal horn neurons sensitization *
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Autonomic (diabetic) neuropathy
See also ANS
ENTERIC NERVOUS SYSTEM
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Achalasia (1:100,000)
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Hirschsprung’s d (1:6,000 live births)
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Visceral neuropathy (neuronal intestinal dysplasia, hyperganglionosis, paraneoplastic; Infectious; myopathies)
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Sensory neurons sensitization * *
See also ENS
The sum of these conditions about 40% of the GI patient population