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Main Psyconeurological Disorders Affecting Gastrointestinal Functions

 PSYCHIC
  • Psychiatric disorders
  • Somatization*
  • Health anxiety*
  • Conversion syndrome*
BRAIN
  • Cerebrovascular accidents (USA: 400,000; GI Dysfunctions > 40%)
  • Head injury
  • Movement disorders (Parkinsonism) (70-180/100,000; GI Dysfunctions > 55%)
  • Multiple sclerosis (USA: 250,000; GI Dysfunctions 68%)
  • Cerebral Palsy -Alzheimer’s d (4% population > 65 yrs)
SPINAL CORD
  • Traumatic lesions
  • Spina bifida (1-4/1,000 live births; GI Dysfunctions > 75%)
  • Multiple sclerosis (USA: 250,000; GI Dysfunctions 68%)
AUTONOMIC NERVOUS SYSTEM
  • Sympathetic dysfunction *
  • Parasympathetic dysfunction *
  • Dorsal horn neurons sensitization *
  • Autonomic (diabetic) neuropathy

See also ANS

ENTERIC NERVOUS SYSTEM
  • Achalasia (1:100,000)
  • Hirschsprung’s d (1:6,000 live births)
  • Visceral neuropathy (neuronal intestinal dysplasia, hyperganglionosis, paraneoplastic; Infectious; myopathies)
  • Sensory neurons sensitization * *

See also ENS

The sum of these conditions about 40% of the GI patient population