ANEMGI-ONLUS  Associazione per la NeUroGastroenterologia e la Motilità Gastrointestinale 
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Vomiting and satiety Print E-mail

 Nausea-Vomiting, Postprandial Fullness-Early Satiety


Causes of nausea & vomiting, postprandial fullness & early satiety

  • Parkinson's d and anti-Parkinson therapy
  • Cerebral palsy
  • Gastric neuropathy with stasis

Psychic Diagnosis of nausea & vomiting, postprandial fullness & early satiety

    all patients

  • *upper GI endoscopy to exclude structural alterations
  • *gastric emptying tests, electrogastrography
  • specific patients

  • *autonomic tests, manometry

Management of nausea & vomiting, postprandial fullness & early satiety

Parkinson's d

    In Parkinson's d gastric emptying time:
    a) plays a relevant role in controlling the access of levodopa tablets to its absorptive sites in the small bowel and thus to an efficient management of the neurological manifestations;
    b) can be delayed for the disease itself and for the antiparkinson therapy with consequent GI symptoms and worsening in the control of the neurological manifestations.

  • Optimize antiparkinson therapy (dopamine agonists and anticholinergics delay gastric emptying)
  • Drugs to accelerate gastric emptying of levodopa tablets: domperidone (also anti-nausea), cisapride
  • Peripheral dopamine antagonists and/or prokinetics which accelerate normal gastric emptying
  • Liquid levodopa -

Other neurological disorders

    Gastric stasis

  • cisapride
  • Motilides

  • Nausea/vomiting

  • Dopamine-antagonists:Metoclopramide, levosulpiride, domperidone
  • 5HT3-antagonists

Psychic disorders

    Gastric stasis

  • Specific psycho-therapy
  • Dopamine-antagonists